Previous studies showed that remifentanil-induced anesthesia can inhibit surgical stress response in\nnon-diabetic adult patients and that low-dose glucose loading during anesthesia may attenuate fat catabolism.\nHowever, little is known about the influence of glucose loading on metabolism in elderly patients, whose condition\nmay be influenced by decreased basal metabolism and increased insulin resistance. We hypothesized that, in\nelderly patients, intraoperative low glucose infusion may attenuate the catabolism of fat without causing harmful\nhyperglycemia during remifentanil-induced anesthesia.\nMethods: Elderly, non-diabetic patients scheduled to undergo elective surgery were enrolled and randomized to\nreceive no glucose (0G group) or low-dose glucose infusion (0.1 g/kg/hr. for 1 h followed by 0.05 g/kg/hr. for 1 h;\nLG group) during surgery. Glucose, adrenocorticotropic hormone (ACTH), 3-methylhistidine (3-MH), insulin, cortisol,\nfree fatty acid (FFA), creatinine (Cr), and ketone body levels were measured pre-anesthesia, 1 h post-glucose\ninfusion, at the end of surgery, and on the following morning............
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